Journal of Biological Chemistry (JBC) Impact Factor 2025 – JCR & Overview

The Journal of Biological Chemistry (JBC) is a weekly peer-reviewed scientific journal established in 1905 and published by the American Society for Biochemistry and Molecular Biology (ASBMB). It covers research in biochemistry, molecular biology, cell biology, structural biology, and related disciplines. JBC is one of the longest-running journals in the life sciences and has published foundational research underlying modern molecular biology.

METRICSJBC Impact Factor 2025

According to the Journal Citation Reports 2026 edition (Clarivate, released June 2025), the Journal of Biological Chemistry achieved an Impact Factor of 4.1. This places the journal in Quartile 2 (Q2) within the Biochemistry & Molecular Biology category.

SCOPEWhat Does JBC Publish?

JBC publishes original research articles and reviews in the broad fields of biochemistry and molecular biology. Specific areas of focus include:

• Enzyme mechanisms and kinetics
• Metabolic pathways and regulation
• Signal transduction and cellular communication
• Protein structure, folding, and function
• Lipids, nucleic acids, and carbohydrate biochemistry
• Gene expression and epigenetic regulation
• Cell biology at the molecular level
• Structural biology and biophysics

The journal does not require universal significance; rigorous mechanistic studies that advance biochemical understanding within their specific area are welcome.

SUBMISSIONSubmission and Peer Review Process

Manuscripts are submitted through the ASBMB submission portal. JBC operates a transparent peer-review model where reviewer comments and author responses may be published alongside accepted articles (optional). The editorial board comprises active researchers who evaluate technical rigor, data quality, and the significance of findings within the context of biochemistry and molecular biology.

Average time to first decision ranges from 3–5 weeks depending on the availability of reviewers.

PUBLISHINGOpen Access Policy

ASBMB transitioned JBC to a fully open-access model in 2021. All articles are now published under a Creative Commons CC BY license and are freely available upon publication. Authors pay no subscription fees, and there is no embargo period. This policy change was part of ASBMB’s broader commitment to making biochemical research accessible to the global scientific community.

EDITORIALEditorial Standards and Ethics

JBC follows COPE guidelines and requires authors to deposit structural coordinates and sequencing data in appropriate public repositories before publication. Antibody validation, cell line authentication, and quantification of Western blot data are standard requirements. The journal has issued retractions and corrections in cases of confirmed misconduct.

HISTORYHistorical Significance

Founded in 1905, JBC has published research that laid the groundwork for modern molecular biology, including early work on enzyme kinetics, the discovery of messenger RNA, elucidation of metabolic cycles, and the structural biology of proteins. ASBMB, which has published the journal since 1925, is one of the largest professional organizations in the molecular life sciences.

FAQFrequently Asked Questions