Last Updated on July 16, 2026 by Dr. Bhagat
JOURNAL METRICS·Updated June 2026
Nature Medicine Impact Factor 2025
Nature Medicine Impact Factor 2025 is 79.6 (Q1, General & Internal Medicine, SCIE). Since 1995, this journal has served as the pinnacle of translational medical publishing, connecting molecular discoveries to clinical outcomes with an influence that extends far beyond academic citation counts.
Key Takeaways
- Nature Medicine holds a 2025 Impact Factor of 79.6, among the highest of any primary research journal in medicine.
- Ranked Q1 in General & Internal Medicine, it is the premier venue for translational biomedical research.
- The CiteScore of 88.2 and SJR of 19.5 confirm dominant citation influence across both Web of Science and Scopus.
- With an h-index of 580, the journal has published numerous landmark papers that define modern clinical research directions.
- Published by Springer Nature since 1995; indexed in SCIE, Medline, Scopus, and all major biomedical databases.
CLINICAL IMPACTTranslating 79.6 Into Real-World Medical Influence
An Impact Factor of 79.6 is not merely a numerical achievement. It represents the aggregation of papers that have shaped clinical trial design, redirected drug development pipelines, and informed regulatory decisions. When Nature Medicine publishes a CAR-T cell therapy advance, an obesity drug mechanism, or a CRISPR clinical trial result, the citations that follow come not just from academic labs but from pharmaceutical R&D divisions, clinical guidelines committees, and health policy organizations.
This real-world influence explains why the CiteScore (88.2) runs even higher than the already extraordinary Impact Factor. The four-year Scopus window captures citations from clinical reviews, meta-analyses, and guideline documents that take longer to publish but carry enormous weight. The SJR of 19.5, among the highest in all of science, confirms that Nature Medicine is cited by the most prestigious journals in biomedicine, not just lower-tier specialty titles.
HISTORICAL TRENDNature Medicine IF Trajectory Over Time
| Year | Impact Factor | 5-Year IF | Category Rank |
|---|---|---|---|
| 2025 | 79.6 | ~82.0 | Top 3 in Medicine |
| 2024 | ~75.0 | ~78.0 | Top 3 in Medicine |
| 2023 | ~82.9 | ~80.0 | Top 3 in Medicine |
| 2022 | ~87.2 | ~82.0 | Top 3 in Medicine |
| 2021 | ~65.0 | ~75.0 | Top 5 in Medicine |
The trajectory shows remarkable stability in the upper range of medical journal metrics. The 2021-2022 spike reflected pandemic-era citation patterns, with the metric normalizing toward a sustainable plateau near 80. The 2025 figure of 79.6 represents a healthy rebound, confirming that Nature Medicine’s editorial selection continues to identify research with exceptional clinical relevance.
PUBLICATION PROFILEComplete Metrics Overview
| Metric | Value | Notes |
|---|---|---|
| Impact Factor | 79.6 | JCR 2025 |
| CiteScore | 88.2 | Scopus 2025 |
| SJR | 19.5 | SCImago 2025 |
| h-index | 580 | Lifetime |
| ISSN | 1078-8956 | Print/eISSN |
| Publisher | Springer Nature | Nature Portfolio |
| Established | 1995 | 30+ years |
| Category | General & Internal Medicine | JCR Q1 |
| Article Types | Articles, Reviews, Brief Communications | — |
FREQUENTLY ASKEDFAQs on Nature Medicine
What is the Nature Medicine Impact Factor for 2025?
79.6, placing it among the three highest-impact primary research journals in all of medicine.
Is Nature Medicine higher impact than NEJM or Lancet?
NEJM and Lancet typically carry IFs in the 90-170 range, but they publish a mix of original research and clinical reviews. Nature Medicine focuses on primary translational research and competes at a similar elite tier for original articles.
What is the acceptance rate at Nature Medicine?
Estimated at <8% for original research articles. The journal receives thousands of submissions annually and exercises stringent editorial selection at the prescreening stage.
Does Nature Medicine accept pure basic science?
All manuscripts must demonstrate a clear path to clinical or disease relevance. While mechanistic depth is essential, the journal prioritizes work with translational implications.
What is the APC for open access?
Approximately $11,390 USD for research articles under the open-access model, consistent with Nature Portfolio pricing.
